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However, patients with severe sulfur sensitivities or specific genetic mutations affecting sulfur metabolism (such as CBS gene upregulations) should consult their healthcare provider before initiating supplementation, as they may need to process sulfur pathways carefully

5A) suggests a diminished capacity for GSH synthesis, which is crucial for chelating intracellular copper ionsa key player in cuproptosis induction [31]

Sznt M, Gupte R, Kraus WL, Pacher P, Bai P

Glutathione, one of the most abundant cellular metabolites, maintains cellular environment in reduced state, protecting proteins and iron-sulfur clusters from oxidative stress and is essential for biosynthesis reactions, such as nucleotide synthesis 3